Alzheimer’s Disease: Causes, Diagnosis and Treatments


March 04, 2025
alzheimers-disease-causes-treatments

Memories shape our identity while connecting us with our past experiences. But people suffering from Alzheimer's often struggle to think or remember as they lose their cognitive skills. The journey begins with smaller lapses like forgetting names, addresses, or misplaced items. But the frequency of forgetting things worsens with time and affects daily life. Understanding Alzheimer's disease causes, symptoms, prevention, and treatment is highly recommended, especially for caregivers. Consulting doctors and visiting rehabilitation centers can help patients recover from this situation in the earlier stages.

What is Alzheimer’s Disease?

Considered a progressive neurological disorder and a root cause of dementia, Alzheimer’s causes a decline in cognitive abilities. It mainly affects older adults (above 60) and slowly destroys their memory and thinking skills. With time, the disease worsens and makes it difficult for the patient to perform simple tasks. As the disease progresses, individuals struggle with daily activities, communication, and even recognizing loved ones. While the exact cause is not fully understood, factors like age, genetics, and lifestyle can contribute to its development.

Dementia vs. Alzheimer’s: What is the Difference?

While most people confuse dementia and Alzheimer’s and use these terms interchangeably, they are not the same. Yes, both deal with memory loss, declining thinking, and cognitive abilities, but there are a few key differences between the two.

What is Dementia?

Dementia is not a specific disease but a syndrome caused by different brain disorders. A group of conditions that cause cognitive decline severe enough to interfere with daily life comes under one umbrella called dementia. There are different types of dementia, including Alzheimer’s Disease, Vascular Dementia, Lewy Body Dementia, and Frontotemporal Dementia.

Comparison Between Dementia and Alzheimer’s Disease

Dementia Alzheimer’s Disease
A general term for cognitive decline A specific disease that causes dementia
Can result from multiple conditions Caused by abnormal brain protein buildup
Depends on the type; some forms are reversible Always progressive and worsens over time
Vary depending on the type Starts with memory loss and gradually affects reasoning, speech, and mobility
Depends on the underlying cause Managed with medications, but no cure

What Deficiency Causes Alzheimer’s Disease?

Research suggests that certain nutritional and biochemical deficiencies contribute to the development and progression of Alzheimer’s disease. Here are some major deficiencies linked to the disease:

  • Acetylcholine Deficiency: Essential for memory and learning.
  • Vitamin B12 Deficiency: Supports nerve function, red blood cell production, and brain health.
  • Vitamin D Deficiency: Helps in proper brain functioning and reduces inflammation.
  • Omega-3 Fatty Acids Deficiency: Essential for brain cell communication and reducing inflammation.
  • Magnesium Deficiency: Helps in sending signals to the nervous system and prevents toxic buildup in the brain.
  • Folate (Vitamin B9) Deficiency: Helps in DNA repair and brain function.

Causes of Alzheimer’s Disease: Understanding the Risk Factors

Alzheimer’s disease can result from a mix of genetic, environmental, and lifestyle factors. Some major risk factors include:

  • Genetic factors (genes and family history)
  • Age (most common in people over 65)
  • Brain changes & protein buildup
  • Poor heart health
  • History of severe head trauma or injuries
  • Unhealthy diet and poor lifestyle
  • Exposure to toxins and environmental factors

Types of Alzheimer’s Disease: Understanding the Variants

  • Early-Onset Alzheimer’s Disease: Occurs before the age of 65, generally between 30-60 years old.
  • Late-Onset Alzheimer’s Disease: Affects people 65 and older and develops gradually.
  • Familial Alzheimer’s Disease (FAD): A rare, inherited form caused by specific genetic mutations.
  • Atypical Alzheimer’s Variants: Majorly affect cognitive functioning ability.

Stages of Alzheimer’s Disease: From Early Symptoms to Severe Decline

  • Preclinical Stage: Brain changes begin years before symptoms appear.
  • Mild Cognitive Impairment (MCI): Subtle memory problems.
  • Mild (Early-Stage) Alzheimer’s: Noticeable memory lapses.
  • Moderate (Middle-Stage) Alzheimer’s: Significant memory loss.
  • Severe (Late-Stage) Alzheimer’s: Inability to recognize loved ones.

How is Alzheimer’s Disease Diagnosed?

Diagnosing Alzheimer's at the earliest stages is crucial. Methods include:

  • Medical history & symptom assessment
  • Cognitive & neuropsychological tests
  • Neurological examination
  • Brain imaging tests
  • Blood & biomarker tests
  • Genetic testing (optional)

Can Alzheimer’s Disease Be Prevented?

While prevention is not guaranteed, it can be controlled with early diagnosis and lifestyle management:

  • Maintain a healthy diet
  • Stay physically active
  • Keep your brain engaged
  • Manage cardiovascular health
  • Get quality sleep
  • Reduce stress and stay socially active

Frequently Asked Questions

1. Can depression increase the risk of Alzheimer's disease?

Yes, studies suggest that long-term depression increases the risk of Alzheimer’s.

2. Is it safe for someone with Alzheimer's to drink alcohol?

No, alcohol can worsen memory loss, confusion, and cognitive decline in individuals with Alzheimer’s.

3. What factors increase the chances of developing Alzheimer's?

Age, genetics, poor lifestyle, social isolation, heart, and brain problems increase the chances of developing Alzheimer's.

4. Drugs Used in Alzheimer’s Disease Treatment

Cholinesterase inhibitors, NMDA receptor antagonists, and new FDA-approved drugs are a few types of drugs used in Alzheimer’s Disease Treatment.

5. How Alzheimer’s Affects Families: Emotional and Financial Impact

From emotional stress to physical strain and financial burden, Alzheimer’s affects families in a lot of unexpected ways.

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